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Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Frontiers of Medicine 2019, Volume 13, Issue 2, Pages 160-188 doi: 10.1007/s11684-018-0629-9

Abstract: Bone tissue engineering (BTE) is a rapidly developing strategy for repairing critical-sized bone defectsHowever, current techniques in bone tissue engineering have not yet reached valid translation into clinical

Keywords： bone tissue engineering stem cell bone scaffold growth factor bone regeneration

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Current progress on scaffolds of tissue engineering heart valves

DONG Nianguo, SHI Jiawei, CHEN Si, HONG Hao, HU Ping

Frontiers of Medicine 2008, Volume 2, Issue 3, Pages 229-234 doi: 10.1007/s11684-008-0043-9

Abstract: Tissue engineering heart valves (TEHV) may be the most promising valve substitute, but the study hasIt is one of the key factors to select an ideal scaffold material in the construction of TEHV.

Keywords： function scaffold promising research engineering

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Cryo-copolymerization preparation of dextran-hyaluronate based supermacroporous cryogel scaffolds for tissue

Dongjiao ZHOU, Shaochuan SHEN, Junxian YUN, Kejian YAO, Dong-Qiang LIN

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 3, Pages 339-347 doi: 10.1007/s11705-012-1209-1

Abstract: Dextran-hyaluronate (Dex-HA) based supermacroporous cryogel scaffolds for soft tissue engineering wereThe obtained cryogel scaffold with 5% (w/w) macromonomer solution had high water permeability (5.1 ×The culture of 3T3-L1 preadipocyte within the scaffold was investigated and observed by SEM.Cells clustered on the pore walls and grew inside the scaffold indicating the Dex-HA cryogel scaffoldcould be a promising porous biomaterial for applications in tissue engineering.

Keywords： cryogel scaffold tissue engineering dextran hyaluronate 3T3-L1 preadipocyte

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Three-dimensional reconstruction of light microscopy image sections: present and future

Yuzhen Wang,Rui Xu,Gaoxing Luo,Jun Wu

Frontiers of Medicine 2015, Volume 9, Issue 1, Pages 30-45 doi: 10.1007/s11684-014-0337-z

Abstract: Three-dimensional (3D) image reconstruction technologies can reveal previously hidden microstructures in human tissuesectioning remains one of the most powerful methods for accurate high-resolution representation of tissueComputer technologies can produce 3D representations of interesting human tissue and organs that haveimaged, and segmented for 3D visualization. 3D reconstruction also has great potential in the fields of tissueThis article outlines the most common methods for 3D tissue section reconstruction.

Keywords： microtomy 3D imaging computer-assisted image processing 3D printing tissue scaffold

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Effect of incorporating Elaeagnus angustifolia extract in PCL-PEG-PCL nanofibers for bone tissue engineering

Vahideh R. Hokmabad, Soodabeh Davaran, Marziyeh Aghazadeh, Effat Alizadeh, Roya Salehi, Ali Ramazani

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 1, Pages 108-119 doi: 10.1007/s11705-018-1742-7

Abstract: ϵ-caprolactone) (PCL-PEG-PCL/EA) nanofibers and their potential applications for bone tissueThese results suggest that PCL-PEG-PCL/EA nanofibers might have potential applications for bone tissue

Keywords： Elaeagnus angustifolia scaffold electrospinning human dental pulp stem cell tissue engineering

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A Review on the 3D Printing of Functional Structures for Medical Phantoms and Regenerated Tissue and

Kan Wang, Chia-Che Ho, Chuck Zhang, Ben Wang

Engineering 2017, Volume 3, Issue 5, Pages 653-662 doi: 10.1016/J.ENG.2017.05.013

Abstract: Such new applications demand high-fidelity, patient-specific, tissue-mimicking medical phantoms thatof the art along with new developments and trends in 3D printed functional medical phantoms (i.e., tissue-mimicking

Keywords： 3D printing 3D bioprinting Medical phantom Regenerated tissue/organ Scaffold

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The Fibrillar Matrix: Novel Avenues for Breast Cancer Detection and Treatment Review

Rasha Rezk, Raquel Marín-García, Annica K.B.Gad

Engineering 2021, Volume 7, Issue 10, Pages 1375-1380 doi: 10.1016/j.eng.2021.04.024

Abstract: These fibers increase the mechanical stiffness of the tissue, which has long been used for tumor diagnosisoverview of how the mechanical properties of breast tumor tissues differ from those of normal breast tissue

Keywords： Breast cancer Tissue stiffness Cancer metastasis Cell migration Bioengineered scaffold Viscosity

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Atypical pituitary hormone–target tissue axis

Frontiers of Medicine 2023, Volume 17, Issue 1, Pages 1-17 doi: 10.1007/s11684-022-0973-7

Abstract: non-classical organs were summarized, defined by the novel concept of an “atypical pituitary hormone–target tissueThe continued exploration of the physiology of the “atypical pituitary hormone–target tissue axis” could

Keywords： thyroid-stimulating hormone follicle-stimulating hormone luteinizing hormone adrenocorticotrophic hormone prolactin

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Progress and perspectives of neural tissue engineering

Xiaosong Gu

Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 401-411 doi: 10.1007/s11684-015-0415-x

Abstract: addressed by current therapeutic interventions for these diseases, a novel promising field of neural tissueSeveral important aspects related to tissue engineered nerves, including the theory on their constructionFurthermore, potential research directions for the future development of neural tissue engineering are

Keywords： nerve injury tissue engineering nerve grafts

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The stem cell and tissue engineering research in Chinese ophthalmology

GE Jian, LIU Jingbo

Frontiers of Medicine 2007, Volume 1, Issue 1, Pages 6-10 doi: 10.1007/s11684-007-0002-x

Abstract: Much has been considerably developed recently in the ophthalmic research of stem cell (SC) and tissue

Keywords： available observable neuroregeneration protection function reconstruction

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Decellularized extracellular matrix mediates tissue construction and regeneration

Frontiers of Medicine 2022, Volume 16, Issue 1, Pages 56-82 doi: 10.1007/s11684-021-0900-3

Abstract: Contributing to organ formation and tissue regeneration, extracellular matrix (ECM) constituents providetissue with three-dimensional (3D) structural integrity and cellular-function regulation.prompt stem-cell proliferation and differentiation for 3D organoid construction in vitro or tissueCellular ECM improves 3D culture development in vitro and tissue remodeling during wound healingGaining better insight into ECM derived from either tissue or cells that regulate 3D tissue reconstruction

Keywords： decellularized extracellular matrix 3D culture organoids tissue repair

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Non-closure of the peritoneum and subcutaneous tissue at radical hysterectomy: A randomized controlled

Zhou-Fang XIONG MD, Wei-Hong DONG MD, Ze-Hua WANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 1, Pages 112-116 doi: 10.1007/s11684-010-0016-7

Abstract: conducted a trial to assess the influence of closure or nonclosure of the peritoneum and subcutaneous tissueResults showed that non-closure of the peritoneum and subcutaneous tissue could shorten operation timeOur study revealed that closure of the peritoneum and subcutaneous tissue provides no immediate postoperativeThe practice of closure of the peritoneum and subcutaneous tissue at radical hysterectomy should be questioned

Keywords： cervical cancer radical surgery peritoneum subcutaneous tissue

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Primary cilia in hard tissue development and diseases

Frontiers of Medicine 2021, Volume 15, Issue 5, Pages 657-678 doi: 10.1007/s11684-021-0829-6

Abstract: Hard tissue diseases have a serious effect on human survival and quality of life.mutations present overt changes in the skeletal system, suggesting that primary cilia are involved in hard tissuethrough primary cilia by intraflagellar transport, which affects key signaling pathways during hard tissueIn addition, the cilium-related diseases of hard tissue and the manifestations of mutant cilia in theWe believe that all the findings will help with the intervention and treatment of related hard tissue

Keywords： primary cilia bone mechanical sensing hard tissue cilium-related bone disease tooth

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Stem cell niches and endogenous electric fields in tissue repair

Li LI, Jianxin JIANG

Frontiers of Medicine 2011, Volume 5, Issue 1, Pages 40-44 doi: 10.1007/s11684-011-0108-z

Abstract: of organs, known as the stem cell niche, which is recognized to have an important role in regulating tissueIn wound healing and tissue repair, stem cells are mobilized and recruited to the site of wound, andHere we briefly review the role of stem cell niches and endogenous electric fields in tissue repair,

Keywords： stem cell stem cell niche electric field tissue repair

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Microorganism-derived biological macromolecules for tissue engineering

Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 358-377 doi: 10.1007/s11684-021-0903-0

Abstract: materials from live creatures as new sources to produce innovative smart biomaterials for increasing tissuereconstruction in tissue engineering and regenerative medicine.such as pullulan, alginate, dextran, curdlan, and hyaluronic acid, and their available sources for tissue

Keywords： biological macromolecules regenerative medicine tissue engineering exopolysaccharide carbohydrate